It won't cause any issues to the rest of the world. You might find it inadvertently starts the quest associated with it. That is because some of those areas, especially the Helgen dungeon, have boxes set up around certain choke points. When you walk in them, it automatically sets a specific quest stage. You can only see them in the CK of course, and otherwise they don't do anything. If the quest has not been started yet, I am not sure if it will automatically start it or not. Try it and find out.
Aside from that, some things might be weird, or not work, in the area. Some areas have statics that are transformed by quest-specific events. For example, The Forgotten Vale has shrines which start out buried in the ground, and only rise up and become usable when following the Dawnguard main quest. If you don't do the quest, those shrines will never work. Though you can still explore the Vale without them.
Finally, you might pick up a quest-related item, which you then cannot ever put down again without doing the quest. Though you can use the console to get rid of those.
I have done this is some places. Several of my characters have gone up to the top of High Hrothgar for example, with the main quest disabled. All it really takes is using the CK to disable to the collision box at the far left of the Greybeard's fortress, which blocks a little ledge that goes around the place. Or using the TCL command in the console of course. After that all you need is the Clear Skies shout, which I turned into an ordinary spell long ago. You never see a Greybeard, never see a dragon, fight some monsters on the way up, and get the Notched Pickaxe at the very top, along with some ore veins
This post has been edited by SubRosa: Jan 31 2015, 08:09 PM
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