QUOTE(ghastley @ May 21 2015, 05:51 PM)

Dead is Dead is a separate issue. I don't do that because I don't think the game suits it. There's a thread on the Bethsoft forums about the times the game just rolls all the dice against you and makes it impossible to win, and I've found a few instances where you're almost guaranteed to lose, even without the random factor.
For example, Orchendor is immune to magic. 100% resistance, so a pure mage can't touch him. If Mellewen hadn't just done the Dawngaurd quests, and had Serana and Auriel's bow with her, she'd have been "without a paddle". But then again, if I played DiD, I'd never roll a pure mage, and a part of the game would be locked off. She gets one-shot killed by Draugr Deathlord archers even with triple Ebonyflesh active, just because she has little health. We've seen a few melee opponents who need to be dodged, too, as she can only drain their health so fast, and some of them can damage her faster than she gets it back.
Yes, I've noticed this in a few places, but the only time I've been able to consistently reproduce it has been in Fallout 3 with the Ant-Agonizer in trying to win the speech challenge. I have well over double the amount of speech needed, but it always takes numerous tries to get her to agree. (However, going to the Mechanist is the opposite, he agrees instantly every single time).
There is no doubt in my mind that there is a random percent condition on the Ant-Agonizer that isn't on the Mechanist in that quest.
True, that example isn't a life or death issue, but it does back up your point about the random selection of quest NPC's that don't follow the protocol, lol.