Wow, didn't know this.
QUOTE
Summary. Cast the following chain of spells: 100(wM wF wC wS)6 (22mana), 100(wM wF wC wS)4 (13mana), 100(wM wF wC wS)2 (6mana), 8(f c s)8 (50mana). The effects amplify each other, and also stack because they are from different spells. The spellchain costs 91mana, and the damage spell is amplified 64 times, for a total of 12,288 damage (135 damage/mana).
Seems there is an entire science behind this!
I'm currently on a break from Oblivion playing X3 - Reunion, but I'm definitely going back to Oblivion sometime, so this info was very useful.
Thanks!