Don't worry about a total reinstall yet. And don't add anything yet. No 4 GB patch yet.
QUOTE(Sakiri @ Nov 28 2018, 03:35 AM)

I don't know if I can uninstall textures or not.
Can't they be uninstalled easily through Bash? If not for some reason, go into the original archive files, and study the structure of the folders which those archives added. Remove them manually. Try to get back to vanilla. See if your game works now. Go into interior and exterior cells, speak to NPCs. See if the issues in your OP are gone. If so, then we'll go from there. If not, you know it's something within your base installation.
I've done this a bunch of times: had some persistent problem (usually CTDs) then tried stripping my game all the way down to vanilla. My game always works fine once it is stripped down. So from there, I start building back up until I find the mod or program which was causing the problem.