I thought I would make a separate mod topic for Fallout 4, since having mods for FO3, NV, and 4 would be a little crowded for one thread.
I started FO4 a few days ago, and quickly came across some must have mods to simply play the game at all.
The Fallout 4 Script Extender - F4SE = Just like the other Beth games, this is a necessary utility.
Mod Organizer 2.0 = The successor to FOMM, for your mod installing and load order sorting needs. Not as good as FOMM, but it is better than nothing.
LooksMenu = This gives you a list of body parts to choose from when creating a character, rather than playing hunt-the-pixel by mousing over every speck of your characters face to see what you can change and what you cannot.
Valkyr Female Face and Body Textures = A much more natural-looking texture. Not as plastic and shiny looking as the vanilla textures are.
Ponytail Hairstyles = From our old friend Azar. Because you never want the vanilla hair in a Bethesda game.
CC's Improved Hair Colors = Because every hair color in the vanilla game is brown.
True Eyes = Improved eye textures.
Face Ripper = For copying faces between characters.
Full Dialog Interface = So you actually know what we are saying.
Dot Instead Of Crosshair = Gives you a small, unobtrusive dot instead of those big ugly crosshairs. As an added bonus you can actually see exactly what you are aiming at.
Moon Size Adjuster = Allows you to make the moon larger. A little bit goes a long way. I went with 1.5x, the smallest increase.
Moon - Beautiful Hi Res Texture = Looks much better than the vanilla moon.
Visible Galaxy 4k = Comes with the stars too. Much better than the vanilla night sky.
No Smoking = Because its gross. Not to mention there would not be any cigarettes or cigars lefter after 200 years.